R. A. FECIK: search on Z-Library

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1

Chiral DNA Gyrase Inhibitors. 3. Probing the Chiral Preference of the Active Site of DNA Gyrase. Synthesis of 10-Fluoro-6-methyl-6,7-dihydro-9-piperazinyl- 2 H -benzo[ a ]quinolizin-20-one-3-carboxylic Acid Analogues

Fecik, Robert A., Devasthale, Pratik, Pillai, Segaran, Keschavarz-Shokri, Ali, Shen, Linus, Mitscher, Lester A.

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 135 KB

english, 2005

2

Total Synthesis and Biological Evaluation of Tubulysin U, Tubulysin V, and Their Analogues

Balasubramanian, Ranganathan, Raghavan, Bhooma, Begaye, Adrian, Sackett, Dan L., Fecik, Robert A.

Journal:

Journal of Medicinal Chemistry

Year:

2009

Language:

english

File:

PDF, 102 KB

english, 2009

3

The search for orally active medications through combinatorial chemistry

Robert A. Fecik, Kristine E. Frank, Elmer J. Gentry, Sanjay R. Menon, Lester A. Mitscher, Hanumaiah Telikepalli

Journal:

Medicinal Research Reviews

Year:

1998

Language:

english

File:

PDF, 504 KB

english, 1998

4

Generation of Novel Pikromycin Antibiotic Products Through Mutasynthesis

Shuchi Gupta, Venkatraman Lakshmanan, Beom Seok Kim, Robert Fecik, Kevin A. Reynolds

Journal:

Year:

2008

Language:

english

File:

PDF, 421 KB

english, 2008

5

ChemInform Abstract: The Search for Orally Active Medications Through Combinatorial Chemistry

R. A. FECIK, K. E. FRANK, E. J. GENTRY, S. R. MENON, L. A. MITSCHER, H. TELIKEPALLI

Journal:

Year:

1998

File:

PDF, 25 KB

1998

6

Formal Total Synthesis of the Polyketide Macrolactone Narbonolide (I).

Lakshmanan Venkatraman, Courtney C. Aldrich, David H. Sherman, Robert A. Fecik

Journal:

Year:

2006

File:

PDF, 9 KB

2006

7

Tubulysin analogs incorporating desmethyl and dimethyl tubuphenylalanine derivatives

Ranganathan Balasubramanian, Bhooma Raghavan, Jaeson C. Steele, Dan L. Sackett, Robert A. Fecik

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2008

Language:

english

File:

PDF, 167 KB

english, 2008

8

A general scheme for synthesis of substrate-based polyketide labels for acyl carrier proteins

Erick K. Leggans, David L. Akey, Janet L. Smith, Robert A. Fecik

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2010

Language:

english

File:

PDF, 408 KB

english, 2010

9

Fatty acid amide hydrolase substrate specificity

Dale L Boger, Robert A Fecik, Jean E Patterson, Hiroshi Miyauchi, Matthew P Patricelli, Benjamin F Cravatt

Journal:

Bioorganic & Medicinal Chemistry Letters

Year:

2000

Language:

english

File:

PDF, 97 KB

english, 2000

10

Natural product biosynthesis moves in vitro

Fecik, Robert A

Journal:

Nature Chemical Biology

Year:

2007

Language:

english

File:

PDF, 2.73 MB

english, 2007

11

Structural basis for macrolactonization by the pikromycin thioesterase

Akey, David L, Kittendorf, Jeffrey D, Giraldes, John W, Fecik, Robert A, Sherman, David H, Smith, Janet L

Journal:

Nature Chemical Biology

Year:

2006

Language:

english

File:

PDF, 607 KB

english, 2006

12

Structural and mechanistic insights into polyketide macrolactonization from polyketide-based affinity labels

Giraldes, John W, Akey, David L, Kittendorf, Jeffrey D, Sherman, David H, Smith, Janet L, Fecik, Robert A

Journal:

Nature Chemical Biology

Year:

2006

Language:

english

File:

PDF, 519 KB

english, 2006

13

Drug-induced sexual dysfunction

Suzanne E. Fecik

Journal:

Medical Update for Psychiatrists

Year:

1998

Language:

english

File:

PDF, 638 KB

english, 1998

14

Cytotoxic Simplified Tubulysin Analogues

Raghavan, Bhooma, Balasubramanian, Ranganathan, Steele, Jaeson C., Sackett, Dan L., Fecik, Robert A.

Journal:

Journal of Medicinal Chemistry

Year:

2008

Language:

english

File:

PDF, 108 KB

english, 2008

15

Formal Total Synthesis of the Polyketide Macrolactone Narbonolide

Venkatraman, Lakshmanan, Aldrich, Courtney C., Sherman, David H., Fecik, Robert A.

Journal:

Journal of Organic Chemistry

Year:

2005

Language:

english

File:

PDF, 151 KB

english, 2005

16

Total Synthesis of Narbonolide and Biotransformation to Pikromycin

Venkatraman, Lakshmanan, Salomon, Christine E., Sherman, David H., Fecik, Robert A.

Journal:

Journal of Organic Chemistry

Year:

2006

Language:

english

File:

PDF, 99 KB

english, 2006

17

Substrate Recognition and Channeling of Monomodules from the Pikromycin Polyketide Synthase

Beck, Brian J., Aldrich, Courtney C., Fecik, Robert A., Reynolds, Kevin A., Sherman, David H.

Journal:

Journal of the American Chemical Society

Year:

2003

Language:

english

File:

PDF, 122 KB

english, 2003

18

Discovery of a Potent, Selective, and Efficacious Class of Reversible α-Ketoheterocycle Inhibitors of Fatty Acid Amide Hydrolase Effective as Analgesics ∇

Boger, Dale L., Miyauchi, Hiroshi, Du, Wu, Hardouin, Christophe, Fecik, Robert A., Cheng, Heng, Hwang, Inkyu, Hedrick, Michael P., Leung, Donmienne, Acevedo, Orlando, Guimarães, Cristiano R. W., Jorge

Journal:

Journal of Medicinal Chemistry

Year:

2005

Language:

english

File:

PDF, 303 KB

english, 2005

19

Chemoenzymatic Synthesis of the Polyketide Macrolactone 10-Deoxymethynolide

Aldrich, Courtney C., Venkatraman, Lakshmanan, Sherman, David H., Fecik, Robert A.

Journal:

Journal of the American Chemical Society

Year:

2005

Language:

english

File:

PDF, 109 KB

english, 2005

20

Advances in Organic Synthesis. Volume 1 Edited by Atta-ur-Rahman and Gerard Jenner. Bentham Science Publishers Ltd., Hilversum, The Netherlands. 2005. vi + 568 pp. 17 × 25 cm. ISBN 90-77527-08. $130.00.

Journal:

Journal of Medicinal Chemistry

Year:

2006

Language:

english

File:

PDF, 12 KB

english, 2006

21

Biochemical Investigation of Pikromycin Biosynthesis Employing Native Penta- and Hexaketide Chain Elongation Intermediates

Aldrich, Courtney C., Beck, Brian J., Fecik, Robert A., Sherman, David H.

Journal:

Journal of the American Chemical Society

Year:

2005

Language:

english

File:

PDF, 296 KB

english, 2005

22

Iterative Chain Elongation by a Pikromycin Monomodular Polyketide Synthase

Beck, Brian J., Aldrich, Courtney C., Fecik, Robert A., Reynolds, Kevin A., Sherman, David H.

Journal:

Journal of the American Chemical Society

Year:

2003

Language:

english

File:

PDF, 46 KB

english, 2003

23

Polyketide Intermediate Mimics as Probes for Revealing Cryptic Stereochemistry of Ketoreductase Domains

Li, Yang, Fiers, William D., Bernard, Steffen M., Smith, Janet L., Aldrich, Courtney C., Fecik, Robert A.

Journal:

ACS Chemical Biology

Year:

2014

Language:

english

File:

PDF, 3.69 MB

english, 2014

24

Practice Errors: MAOIs: Still Here, Still Dangerous

Debra S. Ahmed and Suzanne Fecik

Journal:

AJN American Journal of Nursing

Year:

2000

Language:

english

File:

PDF, 690 KB

english, 2000

25

Chemistry and biology of tubulysins: antimitotic tetrapeptides with activity against drug resistant cancers

Murray, Bryan C., Peterson, Michael T., Fecik, Robert A.

Journal:

Natural Product Reports

Year:

2015

Language:

english

File:

PDF, 706 KB

english, 2015

26

Exceptionally potent inhibitors of fatty acid amide hydrolase: The enzyme responsible for degradation of endogenous oleamide and anandamide

Boger, D. L., Sato, H., Lerner, A. E., Hedrick, M. P., Fecik, R. A., Miyauchi, H., Wilkie, G. D., Austin, B. J., Patricelli, M. P., Cravatt, B. F.

Journal:

Proceedings of the National Academy of Sciences

Year:

2000

Language:

english

File:

PDF, 154 KB

english, 2000

27

Functional Characterization of a Dehydratase Domain from the Pikromycin Polyketide Synthase

Li, Yang, Dodge, Greg J., Fiers, William D., Fecik, Robert A., Smith, Janet L., Aldrich, Courtney C.

Journal:

Journal of the American Chemical Society

Year:

2015

Language:

english

File:

PDF, 726 KB

english, 2015

28

Use of combinatorial and multiple parallel synthesis methodologies for the development of anti-infective natural products

Fecik, R. A., Frank, K. E., Gentry, E. J., Mitscher, L. A., Shibata, M.

Journal:

Pure & Applied Chemistry

Year:

1999

Language:

english

File:

PDF, 212 KB

english, 1999

29

Med Errors: Floating Faux Pas

Debra S. Ahmed and Suzanne Fecik

Journal:

AJN American Journal of Nursing

Year:

1999

Language:

english

File:

PDF, 348 KB

english, 1999

30

Med Errors: The Fatigue Factor

Debra S. Ahmed and Suzanne Fecik

Journal:

AJN American Journal of Nursing

Year:

1999

Language:

english

File:

PDF, 389 KB

english, 1999

31

Tylosin polyketide synthase module 3: stereospecificity, stereoselectivity and steady-state kinetic analysis of β-processing domains via diffusible, synthetic substrates

Fiers, William D., Dodge, Greg J., Li, Yang, Smith, Janet L., Fecik, Robert A., Aldrich, Courtney C.

Journal:

Chemical Science

Year:

2015

Language:

english

File:

PDF, 760 KB

english, 2015

32

Simple Scheme to Predict Transition-State Energies of Dehydration Reactions in Zeolites with Relevance to Biomass Conversion

Fečík, Michal, Plessow, Philipp N., Studt, Felix

Journal:

The Journal of Physical Chemistry C

Year:

2018

Language:

english

File:

PDF, 1.14 MB

english, 2018

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